“Advanced therapies in musculoskeletal regeneration: Novel strategies and challenges for regeneration in compromised...
Klatte-Schulz et al.;Int. J. Mol. Sci.; 2018
The study gives an insight into structural and molecular changes of different pathological processes in Achilles...
Pobloth A-M, et al.; Science Transl. Med.; 2018
For better bone, use softer scaffolds.
Julia Loeffler et. al.; Trends Endocrinol Metab;...
The importance of metabolic pathways and intermediates during bone regeneration.
Reitmaier et al, J Bone Joint Surg Am, Issue 19,...
Use and Limitations of Large Animal Models in Intervertebral Disc Research
Welcome to the Julius Wolff Institute
Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical necessities, we concentrate on basic and applied research in orthopedics and trauma surgery. We primary focus on
- understanding the interaction between movement and loading within joint replacements and during fracture healing,
- enable musculoskeletal mobility,
- identification of underlying principles in compromised healing situations, including delayed bone healing, bone defect healing, muscle trauma, ligament injury and arthrosis.
To do so, we develop innovative therapies by applying biomechanical, mechano-biological and osteo-immunological concepts. Translational approaches are supported by infrastructures of the BCRT.
All our PhD Students and Postdocs are members of the BSRT Graduate School and supported by the mentoring infrastructure.
We have a close interaction with our partner clinics CMSC, with whom we have built an international visible focus on "movement research".