Petersen et al.; Nature Communications; 2018
Biomaterial-induced endochondral ossification to heal bone defects
Eckstein F. et al.; Osteoarthritis Cartilage; 2018
Normal knee joints with contralateral joint space narrowing may serve as human model of early OA
Trepczynski et al.; J Neuroeng Rehabil.; 2018
Antagonistic muscle co-contraction substantially increases in vivo knee contact forces
Klein et al.; Sci Rep.; 2018
MALDI-IMS revealed that early molecular alterations occur largely in the region adjacent to the trauma
Lueckgen et al.; Biomaterials; 2018
Hydrolytically-degradable click-crosslinked alginate hydrogels
Welcome to the Julius Wolff Institute
Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical necessities, we concentrate on basic and applied research in orthopedics and trauma surgery. We primary focus on
- understanding the interaction between movement and loading within joint replacements and during fracture healing,
- enable musculoskeletal mobility,
- identification of underlying principles in compromised healing situations, including delayed bone healing, bone defect healing, muscle trauma, ligament injury and arthrosis.
To do so, we develop innovative therapies by applying biomechanical, mechano-biological and osteo-immunological concepts. Translational approaches are supported by infrastructures of the BCRT.
All our PhD Students and Postdocs are members of the BSRT Graduate School and supported by the mentoring infrastructure.
We have a close interaction with our partner clinics CMSC, with whom we have built an international visible focus on "movement research".
Authors:Christopher Differ graduated
Title:BSRT Student Christopher Differ defended his thesis on the 26 November 2018.
His thesis was entiteled
"Taking NO for an answer: An investigation on the modulatory effects of the Nitric Oxide pathway on Bone Morphogenic Protein 2 signalling and osteoinductive potential".
Deutsche Gesellschaft für Unfallschirurgie
Deutsche Gesellschaf für Unfallchirurgie
Title:Gluteal muscle damage leads to higher in vivo hip joint loads 3 months after total hip arthroplasty
ESB Clinical Biomechanics Award 2018
European Society of Biomechanics
Journal:Philipp Damm, Jip Zonneveld, Sophie Brackertz, Florian Streitparth, Florian Winkler Year:2018;