Comparison of acute and chronic tendon pathologies
Klatte Schulz F. et al., Int J Mol Sci. 2018 Jan 30;19(2). pii: E404. doi: 10.3390/ijms19020404.
When to reimplant after joint infection?
Winkler et at., Arch Orthop Trauma Surg 2019; 139(4):295-303.
Collagen scaffolds negatively impact bone healing ...
Lang A. et al., Acta Biomaterialia 2019; 86:171-184.
Petersen et al.; Nature Communications; 2018
Biomaterial-induced endochondral ossification to heal bone defects
Eckstein F. et al.; Osteoarthritis Cartilage; 2018
Normal knee joints with contralateral joint space narrowing may serve as human model of early OA
Trepczynski et al.; J Neuroeng Rehabil.; 2018
Antagonistic muscle co-contraction substantially increases in vivo knee contact forces
Klein et al.; Sci Rep.; 2018
MALDI-IMS revealed that early molecular alterations occur largely in the region adjacent to the trauma
Lueckgen et al.; Biomaterials; 2018
Hydrolytically-degradable click-crosslinked alginate hydrogels
Moll et al.; Trends in Molecular Medicine; 2019
Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines
Basic and applied research in orthopaedics and trauma surgery
Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical necessities, we concentrate on basic and applied research in orthopedics and trauma surgery.
Understand - the interaction between movement and loading within joint replacements and during fracture healing
Enable - musculoskeletal mobility
Initiate - regeneration in challenging healing situations, such as delayed bone healing, bone defect healing, muscle trauma, ligament injury and arthrosis.
Inspiration - Our research teams have the opportunity to develop their ideas into joint reserach projects with the support of modern team coaching and seed funding provided by the ECRT.
Education - All our PhD Students and Postdocs are members of the BSRT Graduate School and supported by the mentoring infrastructure.
Translation - We develop innovative therapies by applying biomechanical, mechano-biological and osteo-immunological concepts. Translational approaches are supported by infrastructures of the BCRT.
Regeneration - Essential for our clinically motivated research is the close interaction with our partner clinics CMSC with whom we have built a focus on "movement research".
12.11.2019 To 13.11.2019
Animal experiments in science
This course is optional for doctoral researchers at the BSRT
In Life Science the step from the petry dish towards a clinical application often includes animal experiments.
03.12.2019 To 06.12.2019
The Hitchhicker's Guide to regenerative Therapies: The Role of Space and Time in Healing Processes
BSRT Symposium 2019
Much like an intergalactic traveler is dependent on a precise understanding of space and time, regenerative medicine aims at navigating safely through the intricate spatiotemporal microenvironments that determines successful healing.
Authors:Aaron Herrera graduated
Title:BSRT Student Aaron Herrera defended his thesis on the 07 October 2019.
His thesis was entiteled
Curvature-controlled cell orientation and ECM patterning for biomaterial design
Authors:Mark Heyland graduated
Title:JWI Student Mark Heyland defended his thesis on the 07 August 2019.
His thesis was entiteled
Mechanotherapy of Bone Fracture: Adapted Fixation Conditions
Authors:Julia Löffler graduated
Her thesis was entiteled
Impact of the local metabolic milieu on bone fracture healing