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Comparison of acute and chronic tendon pathologies

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Klatte Schulz F. et al., Int J Mol Sci. 2018 Jan 30;19(2). pii: E404. doi: 10.3390/ijms19020404.
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When to reimplant after joint infection?

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Winkler et at., Arch Orthop Trauma Surg 2019; 139(4):295-303.
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Collagen scaffolds negatively impact bone healing ...

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Lang A. et al., Acta Biomaterialia 2019; 86:171-184.
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Petersen et al.; Nature Communications; 2018

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Biomaterial-induced endochondral ossification to heal bone defects
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Eckstein F. et al.; Osteoarthritis Cartilage; 2018

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Normal knee joints with contralateral joint space narrowing may serve as human model of early OA
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Trepczynski et al.; J Neuroeng Rehabil.; 2018

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Antagonistic muscle co-contraction substantially increases in vivo knee contact forces
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Klein et al.; Sci Rep.; 2018

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MALDI-IMS revealed that early molecular alterations occur largely in the region adjacent to the trauma
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Lueckgen et al.; Biomaterials; 2018

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Hydrolytically-degradable click-crosslinked alginate hydrogels
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Moll et al.; Trends in Molecular Medicine; 2019

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Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines

Julius Wolff Institute

Basic and applied research in orthopaedics and trauma surgery

Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical necessities, we concentrate on basic and applied research in orthopedics and trauma surgery.

Our Focus

Understand - the interaction between movement and loading within joint replacements and during fracture healing

Enable - musculoskeletal mobility

Initiate - regeneration in challenging healing situations, such as delayed bone healing, bone defect healing, muscle trauma, ligament injury and arthrosis.

JWI Network

Inspiration - Our research teams have the opportunity to develop their ideas into joint reserach projects with the support of modern team coaching and seed funding provided by the ECRT.

Education - All our PhD Students and Postdocs are members of the BSRT Graduate School and supported by the mentoring infrastructure.

Translation - We develop innovative therapies by applying biomechanical, mechano-biological and osteo-immunological concepts. Translational approaches are supported by infrastructures of the BCRT.

Regeneration - Essential for our clinically motivated research is the close interaction with our partner clinics CMSC with whom we have built a focus on "movement research".

Current Events

Congratulations

Authors:Mark Heyland graduated
Title:JWI Student Mark Heyland defended his thesis on the 07 August 2019.

His thesis was entiteled
Mechanotherapy of Bone Fracture: Adapted Fixation Conditions
Year:2019;
Authors:Julia Löffler graduated
Title:BSRT Student Julia Löffler defended her thesis on the 09 April 2019.

Her thesis was entiteled
Impact of the local metabolic milieu on bone fracture healing
Year:2019;
Authors:Dr. Philippe Moewis received for
Title:Does a total knee arthroplasty design with a lateral pivot lead to a correspondent knee joint kinematic?

1. Poster Prize at the 11th Kongress of the German Society for Biomechanic
Year:2019;
Authors:Philipp Moroder received for
Title:Latarjet Procedure versus Iliac-Crest Bone Graft Transfer for Treatment of Anterior Shoulder Instability with Glenoid Bone Loss: a Prospective Randomized Trial.

the Neer-Prize
of the American Shoulder and Elbow Surgeons Association
Year:2019;