• research_pub_petersen_natcommuns.jpg

    Petersen et al.; Nature Communications; 2018

    Biomaterial-induced endochondral ossification to heal bone defects

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    Eckstein F. et al.; Osteoarthritis Cartilage; 2018

    Normal knee joints with contralateral joint space narrowing may serve as human model of early OA

  • Trepczynski_et_al_2018_Co-Contraction.png

    Trepczynski et al.; J Neuroeng Rehabil.; 2018

    Antagonistic muscle co-contraction substantially increases in vivo knee contact forces

  • Klein_et_al_-_HP_JWI_new.png

    Klein et al.; Sci Rep.; 2018

    MALDI-IMS revealed that early molecular alterations occur largely in the region adjacent to the trauma

  • Paper_Lückgen.tif

    Lueckgen et al.; Biomaterials; 2018

    Hydrolytically-degradable click-crosslinked alginate hydrogels

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    Moll et al.; Trends in Molecular Medicine; 2019

    Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines

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    Latest Publications

Julius Wolff Institute

Basic and applied research in orthopaedics and trauma surgery

Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical necessities, we concentrate on basic and applied research in orthopedics and trauma surgery.

Our Focus

Understand - the interaction between movement and loading within joint replacements and during fracture healing

Enable - musculoskeletal mobility

Initiate - regeneration in challenging healing situations, such as delayed bone healing, bone defect healing, muscle trauma, ligament injury and arthrosis.

JWI Network

Inspiration - Our research teams have the opportunity to develop their ideas into joint reserach projects with the support of modern team coaching and seed funding provided by the ECRT.

Education - All our PhD Students and Postdocs are members of the BSRT Graduate School and supported by the mentoring infrastructure.

Translation - We develop innovative therapies by applying biomechanical, mechano-biological and osteo-immunological concepts. Translational approaches are supported by infrastructures of the BCRT.

Regeneration - Essential for our clinically motivated research is the close interaction with our partner clinics CMSC with whom we have built a focus on "movement research".


  • Tobias Winkler received for

    Immunomodulatory placental-expanded, mesenchymal stromal cells improve muscle function following hip arthroplasty

    the Science Award 2018
    of the "Deutsche Gesellschaft für Endoprothetik" and the "Stiftung Endoprothetik"


  • Viktor Janz received for

    Rapid detection of periprosthetic joint infection using a combination of 16s rDNA polymerase chain reaction and lateral flow immunoassay: A Pilot Study

    The Award for Basic Science 2018
    of the "Deutsche Gesellschaft für Endoprothetik" and the "Stiftung Endoprothetik"

    Authors of the Publication: Janz V, Schoon J, Morgenstern C, Preininger B, Reinke S, Duda G, Breitbach A, Perka C, Geissler S 2018;

  • Johannes Keller received for

    Lokale und systemische Regulations- und Kommunikationsmechanismen im Knochenstoffwechsel

    the Hans-Liniger Prize 2018
    of the German Society for Trauma Surgery (DGU)


  • Claudia Schlundt received for

    Impact of the adaptive immune system in bone fracture healing

    the PhD Thesis Award 2018
    of the German Society for Trauma Surgery (DGU)


    Schlundt, Claudia