• Klatte-Schulz_et_al_2018-940x400.jpg

    Comparison of acute and chronic tendon pathologies

    Klatte Schulz F. et al., Int J Mol Sci. 2018 Jan 30;19(2). pii: E404. doi: 10.3390/ijms19020404.

  • Winkler2018-940x420.png

    When to reimplant after joint infection?

    Winkler et at., Arch Orthop Trauma Surg 2019; 139(4):295-303.

  • Lang_et_al_2019.jpg

    Collagen scaffolds negatively impact bone healing ...

    Lang A. et al., Acta Biomaterialia 2019; 86:171-184.

  • research_pub_petersen_natcommuns.jpg

    Petersen et al.; Nature Communications; 2018

    Biomaterial-induced endochondral ossification to heal bone defects

  • Publication_Duda.png

    Eckstein F. et al.; Osteoarthritis Cartilage; 2018

    Normal knee joints with contralateral joint space narrowing may serve as human model of early OA

  • Trepczynski_et_al_2018_Co-Contraction.png

    Trepczynski et al.; J Neuroeng Rehabil.; 2018

    Antagonistic muscle co-contraction substantially increases in vivo knee contact forces

  • Klein_et_al_-_HP_JWI_new.png

    Klein et al.; Sci Rep.; 2018

    MALDI-IMS revealed that early molecular alterations occur largely in the region adjacent to the trauma

  • Lueckge_at_al._2018.jpg

    Lueckgen et al.; Biomaterials; 2018

    Hydrolytically-degradable click-crosslinked alginate hydrogels

  • Moll_et_al_2019.jpg

    Moll et al.; Trends in Molecular Medicine; 2019

    Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines

Julius Wolff Institute

Julius Wolff Institute

Basic and applied research in orthopaedics and trauma surgery

Basic and applied research in orthopaedics and trauma surgery

Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical necessities, we concentrate on basic and applied research in orthopedics and trauma surgery.

Our Focus

Understand - the interaction between movement and loading within joint replacements and during fracture healing

Enable - musculoskeletal mobility

Initiate - regeneration in challenging healing situations, such as delayed bone healing, bone defect healing, muscle trauma, ligament injury and arthrosis.

JWI Network

JWI Network

Inspiration - Our research teams have the opportunity to develop their ideas into joint reserach projects with the support of modern team coaching and seed funding provided by the ECRT.

Education - All our PhD Students and Postdocs are members of the BSRT Graduate School and supported by the mentoring infrastructure.

Translation - We develop innovative therapies by applying biomechanical, mechano-biological and osteo-immunological concepts. Translational approaches are supported by infrastructures of the BCRT.

Regeneration - Essential for our clinically motivated research is the close interaction with our partner clinics CMSC with whom we have built a focus on "movement research".

Current Events

There are currently no events of this facility.


  • Ansgar Petersen received for

    A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects

    the basic research award 2019
    of the German Society for Orthopaedics and Trauma Surgery (DGOU)


  • Gerg Bergmann received for

    his life's work in which he has rendered outstanding services to the development of German orthopaedics in a special way

    the Georg Hohmann badge
    The presentation of the plaque took place with a short appreciation of the special merits at the annual congress of the DGOOC.


  • Laia Albiol is graduated

    BSRT student Laia Albiol defended her thesi on the 01. November 2019

    Her thesis was entitled
    "Influence of sost deficiency and skeletal maturation on the bone modeling and remodeling response to mechanical loading”


  • Sebastian Wendler graduated

    BSRT student Sebastian Wendler defended his thesis on 18 October 2019

    His thesis was entiteled
    "Delayed local delivery of synsthetic prostacyclin to modulate inflammatory processes in support of bone regeneration"


  • Aaron Herrera graduated

    BSRT student Aaron Herrera defended his thesis on 07 October 2019

    His thesis was entitled
    "Curvature-controlled cell orientation and ECM patterning for biomaterial design"