Julius Wolff Institute (JWI) -
Center for Musculoskeletal Biomechanics and Regeneration at the BIH

The institute stands in the tradition of Julius Wolff, the founder of the orthopedic clinic in the Charité. The theory of Julius Wolff – the so-called "Wolff's law" – shows the correlation between mechanics and medicine, and explains that the form and structure of bone constantly adapts to mechanical loading. Wolff's law is still highly relevant for musculoskeletal research today.

Using Wolff's findings as a basis, we strudy the influence how biology is affected by mechanical stimulation. For example, we study stresses and strains on the musculoskeletal system of patients and athletes. Furthermore, we are investigating the regeneration processes of bone, cartilage, muscles and ligaments and analyze the loads acting on joints and bones during these processes.

Our research benefits patient care and stimulates innovations for implants in the area of joint replacement as well as fracture healing. Through a better understanding of biological processes during healing, we were able to develop new therapies and products for accelerating healing processes. In order to translate our findings into practice we closely collaborate with national and international partners from industry and science.