Julius Wolff Institute

Director Univ.- Prof. Dr.-Ing. Georg Duda

As a research institute we run applications and basic research in the fields of orthopedics and trauma surgery. Our main research field is the regeneration and biomechanics of the musculoskeletal system as well as the improvement of joint replacement.

Cutting edge musculoskeletal research

The Julius Wolff Institute is within the university structure of the Charité - Universitätsmedizin Berlin assigned to the CharitéCentrum 9.
Our institute brings together national and international scientists from different areas of musculoskeletal research and allows by scientific and personal links with research institutions the scientific exchange of international informations and experiences.

The institute is headed by Prof. Dr. Georg Duda and his deputy, Prof. Dr. Georg Bergmann.

The Julius Wolff Institute was established in 2008, founded by a merger of the research laboratory of the Center of Musculoskeletal Surgery of the Charité (CMSC) and the Clinical Biomechanics Laboratory of the Charité
The institute stands in the tradition of Julius Wolff, the founder of the orthopedic clinic in the Charité. The theory of Julius Wolff – the so-called "Wolff's law" – shows the correlation between mechanics and medicine, and explains that the form and structure of bone constantly adapts to mechanical loading.
The theory of Wolff is still highly relevant for musculoskeletal research today. The institute takes Wolff's findings as a starting point and investigates the influence of mechanical stimulation on biological reactions. For example, we study stresses and strains on the musculoskeletal system of patients and athletes. Furthermore, we are engaged in the regeneration of bone, cartilage, muscles and ligaments and analyze the direct loadings in joints and bones.

In order to translate our findings into practice we tightly collaborate with the Center for Musculoskeletal Surgery (CMSC), further clinical departments of the Charité, and with national and international partners from industry as well as science. Because of its outstanding research and comprehensive collaborations, the Julius Wolff Institute plays a significant role within various research networks.

Our research benefits patient care and stimulates innovations for implants in the area of joint replacement as well as fracture healing. Through a better understanding of biological processes during healing, we were able to develop new therapies and products for accelerating healing processes.