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27.06.2011

Britt Wildemann receives APOA Pfizer Best Scientific Paper Award

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Wildemann and her team received the award for the publication about the realization of a sequential release of factors from an implant coating.

Britt Wildemann, scientist at the Berlin-Brandenburg Center for Regenerative Therapies (BCRT) and Julius Wolff Institute, was awarded with the APOA-Pfizer Best Scientific Paper Award 2011. Professor Wildemann and her team received the award for the publication "Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implants", published in the "Journal of Controlled Released".

The awarded study is part of the PhD thesis from Catrin Strobel and is funded by the SFB 760 "Biomechanics and biology of musculoskeletal regeneration". Goal of the study was the realization of a sequential release of factors from an implant coating. The implant serves than not only for fracture stabilization but also as a drug delivery system. The timely controlled release allows the early release of antibiotics for infection prophylaxis and a delayed release of growth factors to stimulate the healing process. This approach allows a controlled and tuneable release of different factors directly at the fracture site without the application of further carrier.  

The Award is announced annually from the Asia Pacific Orthopaedic Association (APOA) and carries a value of US$ 5.000.

Links

Strobel C, Bormann N, Kadow A, Schmidmaier G, Wildemann B
Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implants.
J Control Release. 2011 Nov 30;156(1):37-45



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