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Charité and DIZG: Together for advanced tissue replacement

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Cooperation agreement seals close cooperation for further development of tissue and cell transplants

The Julius Wolff Institute of the Charité - Universitätsmedizin Berlin and the non-profit German Institute for Cell and Tissue Replacement (DIZG) are jointly researching the further development of tissue and cell transplants. With a cooperation agreement, the two institutions have now sealed their close cooperation.

The aim of the cooperation is to improve treatment options for disease-related or accident-related bone defects, especially for complex and difficult treatment situations in trauma surgery and orthopaedics. Both institutes are leaders in the field of tissue regeneration. While the Julius Wolff Institute is primarily concerned with application-oriented, translational research projects for the regeneration of the musculoskeletal system, the non-profit DIZG produces human avital tissue transplants and autologous cell culture transplants and is constantly further developing these transplants obtained from tissue donations. The aim of the cooperation is to transfer findings from basic research into clinical practice and, conversely, to transfer questions from everyday clinical practice to the laboratories.

"The close exchange between research, clinic and manufacturer is a great opportunity to optimise therapies for the treatment of the most severe tissue defects and to expand the variety of transplants so that we can help even more people with tailor-made therapies in the future," says DIZG Managing Director Jürgen Ehlers. Project leader Prof. Dr. Britt Wildemann, professor at Berlin-Brandenburg Centre for Regenerative Therapies (BCRT) and active at the Julius Wolff Institute, adds: "With the recently concluded cooperation agreement, we are reinforcing our long-standing successful cooperation with the DIZG. I am convinced that the research projects carried out within the framework of the cooperation agreement will bear fruit and ultimately benefit the patients". The BCRT, founded in 2006 as an alliance of the Charité - Universitätsmedizin Berlin and the Helmholtz Association, continuously advises and accompanies the JWI research group and ensures that the research results can quickly be transferred into clinical application.

The German Institute for Cell and Tissue Replacement (DIZG) is a non-profit manufacturer of allogeneic tissue transplants and autologous cell cultures. The aim is to offer as many people as possible with severe tissue defects an improved perspective on healing from the donor's gift. For this reason, the institute, founded in Berlin in 1993, promotes tissue donation, researches and develops transplant diversity on an ongoing basis. In the meantime, every year almost 30,000 patients with severe injuries benefit from about 250 different types of transplants from the DIZG laboratories. The German Institute for Cell and Tissue Replacement


DIZG Jahresbericht 2013 (Seite 10)


Julius Wolff Institute
Phone: +49 30 450 559 048
E-Mail: jwi(at)
Augustenburger Platz 
113353 Berlin

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