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Dr. med. Frank Graef

Junior Clinician Scientist - Molecular Traumatology

Center for Musculoskeletal Surgery
Charité - Universitätsmedizin Berlin
Föhrer Str. 15
13353 Berlin

Campus / internal address:
Südstraße 2

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Expertise

Academic career

Since 01/2016: Resident at the Center for Musculoskeletal Surgery, Charité University Hospital Berlin
Since 01/2018: Junior Clinician Scientist

Academic degrees

Dr. med.

Education 

2009-2015: Medical School, Charité University Hospital Berlin

Selected presentations

Graef F, Locher R, Schaser K, Garbe A, Haas N, Duda G, Kleber C, Tsitsilonis S.
Quantitative micro-CT und biomechanische Analyse der Frakturheilung von Leptin Knockout-Mäusen mit und ohne Schädel-Hirn-Trauma
Deutscher Kongress für Orthopädie und Unfallchirurgie 2014, Berlin (Vortrag)

Graef F, Locher R, Schaser K, Garbe A, Haas N, Duda G, Kleber C, Tsitsilonis S.
Die Knochenheilung in Leptin-defizienten Mäusen ist reduziert und zeigt keine Verbesserung durch zusätzliches Schädel-Hirn-Trauma.
Osteologie 2015, Berlin (Vortrag)

Graef F, Locher R, Schaser K, Garbe A, Haas N, Duda G, Kleber C, Tsitsilonis S.
Micro computed-tomography and biomechanical testing analysis show decreased fracture healing in leptin-deficient mice which does not increase after Controlled Cortical Impact Injury
4th Joint Meeting of European Calcified Tissue Society (ECTS) and the International Bone and Mineral Society (IBMS) 2015, Rotterdam (Poster-Präsentation)

Graef F, Zaslansky P, Seemann R, Garbe A, Keller J, Tsitsilonis S.
Analyse der Knochenmikro-Architektur Leptin-defizienter und Wildtyp-Mäuse mittels Mikro-CT
Deutscher Kongress für Orthopädie und Unfallchirurgie 2016, Berlin (Vortrag)

Memberships

  • Deutsche Gesellschaft für Orthopädie und Unfallchirurgie
  • AO Trauma

Third-party funding

Berlin Institute of Health, Junior Clinician Scientist program

Publications

Graef F, Seemann R, Garbe A, Schmidt-Bleek K, Schaser KD, Keller J, Duda G, Tsitsilonis S.
Impaired fracture healing with high non-union rates remains irreversible after traumatic brain injury in leptin-deficient mice.
J Musculoskelet Neuronal Interact. 2017 Jun 1;17(2):78-85. 

Seemann R, Graef F, Garbe A, Keller J, Huang F, Duda G, Schmidt-Bleek K, Schaser K-D, Tsitsilonis S. Leptin-deficiency eradicates the positive effect of traumatic brain injury on bone healing: histological analysis in a combined trauma mouse model.
J Musculoskelet Neuronal Interact. 2017 Nov.

Wichlas F, Tsitsilonis S, Disch AC, Haas NP, Hartmann C, Graef F, Schwabe P.
Long-term functional outcome and quality of life after successful surgical treatment of tibial nonunions.
Int Orthop. 2015 Mar;39(3):521-5.