Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration 

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Research at the JWI

Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical needs, we focus on basic and applied research in orthopedics and trauma surgery.

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Biology of musculoskeletal regeneration

Musculoskeletal Cell Biology
headed by Sven Geißler

We investigate the biology of adult stem cells, immune cells, endothelial precursors and fibroblasts as well as their possible role in musculoskeletal tissue regeneration.

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Molecular Traumatology
headed Serafim Tsitsilonis

We investigate the molecular and cellular bases of clinically relevant questions in musculoskeletal surgery, focusing on pharmacologically exploitable signaling events.

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Bone Healing
headed by Katharina Schmidt-Bleek

After an injury, bone can usually heal. However, despite good medical care, 5-20% of all fractures take a long time to heal or fail to heal at all. The aim of our research is to find a meaningful solution strategy for these patients.

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Tendon and Bone Regeneration
headed by Franka Klatte

In addition to bone regeneration, the aim of our working group is to better understand tendon regeneration and thus to develop therapies for the patient that are improved in perspective.

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Musculoskeletal Advanced Therapies
headed by Tobias Winkler

Since 2006 we have been working on translational therapies in the field of musculoskeletal regeneration with the aim to bring innovative regenerative approaches to the patient.

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