Cellular BioMechanics & BioMaterials
We explore the interaction between cells, their surrounding matrix, and biomaterials for the development of new muskuloskeletal treatment strategies. We design micro-environments that provide specific mechanical, geometrical, and biochemical signals to support and control endogenous healing cascades.
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Publications
- Authors:Duda GN, Geissler S, Checa S, Tsitsilonis S, Petersen A, Schmidt-Bleek K
Journal:Nat Rev Rheumatol Year:2023; Volume:19Issue:(2):Pages:78-95.
Title:The decisive early phase of bone regeneration - Authors:Brauer E, Lange T, Keller D, Görlitz S, Cho S, Keye J, Gossen M, Petersen A, Kornak U
Journal:Aging Cell Year:2022;
Title:Dissecting the influence of cellular senescence on cell mechanics and extracellular matrix formation in vitro - Authors:Tortorici M, Brauer E, Thiele M, Duda GN, Petersen A
Journal:Front Bioeng Biotechnol Year:2022; Volume:10
Title:Characterizing cell recruitment into isotropic and anisotropic biomaterials by quantification of spatial density gradients in vitro - Authors:Tortorici M, Petersen A, Duda GN, Checa S
Journal:Front Bioeng Biotechnol Year:2022; Volume:10
Title:The Degradation of Synthetic Polymeric Scaffolds With Strut-like Architecture Influences the Mechanics-dependent Repair Process of an Osteochondral Defect in Silico - Authors:Tortorici M, Gayer Ch, Torchio A, Cho S, Schleifenbaum JH, Petersen A
Journal:Mater Sci Eng C Mater Biol Appl Year:2021; Volume:123
Title:Inner strut morphology is the key parameter in producing highly porous and mechanically stable poly(ε-caprolactone) scaffolds via selective laser sintering - Authors:Tortorici M, Petersen A, Ehrhart K, Duda GN, Checa S
Journal:Front Bioeng Biotechnol Year:2021; Volume:9
Title:Scaffold-Dependent Mechanical and Architectural Cues Guide Osteochondral Defect Healing in silico - Authors:Schreivogel S, Kuchibhotla V, Knaus P, Duda GN, Petersen A
Journal:J Tissue Eng Regen Med Year:2019;
Title:Load-induced osteogenic differentiation of mesenchymal stromal cells is caused by mechano-regulated autocrine signaling - Authors:Herrera A, Hellwig J, Leemhuis H, von Klitzing R, Heschel I, Duda GN, Petersen A
Journal:Mater Sci Eng C Mater Biol Appl Year:2019; Volume:103
Title:From macroscopic mechanics to cell-effective stiffness within highly aligned macroporous collagen scaffolds. - Authors:Herrera A, Hellwig J, Leemhuis H, von Klitzing R, Heschel I, .Duda GN. Petersen A
Journal:Materials Science and Engineering: C Year:2019; Volume:103
Title:From macroscopic mechanics to cell-effective stiffness within highly aligned macroporous collagen scaffolds - Authors:Brauer E, Lippens E, Klein O, Nebrich G, Schreivogel S, Korus G, Duda GN, Petersen A
Journal:Advanced Science Year:2019; Volume:6Issue:(9):Pages:1801780.
Title:Collagen fibrils mechanically contribute to tissue contraction in an in vitro wound healing scenario