Bone Remodeling around Implants

Periprosthetic bone loss remains a persistent concern in the long term survival of primary total hip arthroplasty (THA). Changes in the loading conditions, geometry and material properties after THA alter the internal mechanical environment within the bone, stimulating a periprosthetic bone remodelling response which usually leads to a net bone loss. This is of major concern, particularly in the proximal Gruen zones, which are critical for implant stability and Iongevity. Using computer modeling techniques, we investigate the mechanics of total hip replacement and explore the limits of current designs.