Translation of Cell therapy for Musculoskeletal Orthopedics

Priv.-Doz. Dr. med. Tobias Winkler

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Completed

A Phase I/II, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Intramuscular Injections of Allogeneic PLX-PAD Cells for the Regeneration of Injured Gluteal Musculature (GM) after Total Hip Arthroplasty (THA)

ClinicalTrials.gov Identifier: NCT01525667

Under Preparation

Clinical Problem. Female patient after total hip revision arthroplasty. Satisfying X-ray – but degeneration of the periarticular muscle due to repeated surgeries leading to instability of the joint and limping (damaged gluteus muscles indicated by arrowheads and asterisk)

Follow-up clinical trial using allogeneic cell therapy in skeletal muscle injuries